Isco and Gareth Bale scored, as Real Madrid ran out 2-0 victors in Zidane's first game since his return to the Bernabeu.
Both players, who had had it difficult under the previous manager, scored in the second half, having been recalled to the starting line-up by the French boss.
Isco, who played very little football under Solari, opened the scoring after the hour when he side-footed Benzema's pass after a quick counter attack by the Galacticos.
Gareth Bale, who twice escaped a sending off, would then wrap up the points when he fired in on the near post after some good work in the build-up by Marcelo (another one who was ostracized by the former manager).
Madrid have now moved two points closer to their City rivals Atleti who will play against Athletic Bilbao later on Saturday.