Super Eagles right-back, Shehu Abdullahi, was one of three players that were missing in training as the Nigerian team prepared for Guinea.
The defender, who picked up a hamstring injury and was substituted in Nigeria's win over Burundi, was one of three absentees in the Eagles closed door training earlier today in Alexandria.
Jamilu Collins and Samul Kalu were the other two players that were missing from action as the West Africans trained for Wednesday's game.
Jamilu had missed the opening game due to injury and was replaced in the starters line up by Ola Aina who put in a fine performance against the Swallows.
Samuel Kalu was an onlooker from the stands in that game after recovering from dehydration that caused him to collapse in training last Friday.
The Super Eagles are well placed to qualify from group B where they currently sit top with 3 points.
Coach Gernot Rohr is expected to make some changes to his team for the game against the National Elephants who played a 2-2 draw against Madagascar in their opening game.